Krztusiec

Zarys historyczny leczenia krztuśca

Źródło: Zofia Podgóska-Klawe, “Choroby dzieci i sposoby ich leczenia przed stu laty w Warszawie“, Pediatria Polska 1969, zob. Choroby dzieci i pseudoleczenie w połowie XIX wieku w Warszawie


Źródło: “Krztusiec”, Szczepańska 1962

Źródło: “Rekomendacje postępowania w pozaszpitalnych zakażeniach układu oddechowego 2010“ (lektura obowiązkowa dla rodziców!)

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(North Carolinians confused as to why all 103 cases fully vaxed and no unvaccinated kids got it):

(Excerpt): … (the) outbreak…has grown to include more than 103 cases…..SHAPLEY-QUINN SAID there’s no instance of a child who had not been vaccinated getting pertussis….

(SHOT DOWN !!!) Board member Tony Rose had asked for information about the number of students who don’t get vaccinations because of religious or other reasons. “I think it’s 15 kids in your entire system (who) have an exemption for medical or religious reasons,” Shapley-Quinn said. None of the pertussis cases involved those students, she said.

Bass said the system has a “really good vaccination rate,” which “raises questions about the vaccine itself” and its effectiveness in preventing the disease.

http://web.archive.org/web/20120424095716/http://www.thetimesnews.com/news/school-53424-department-health.html

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„PARENTS across Australia will no longer receive free whooping cough vaccinations because it is not effective in protecting newborns from the potentially deadly illness, a parliamentary committee has heard.” „The PBAC, which is totally independent and very expert, has determined that there is no clinical effectiveness of this strategy,” Professor Brook said. He said this had made it clear the cocooning strategy should not be continued. „So all jurisdictions who have been in this program will be effectively ceasing the cocooning strategy as of the end of June this year.” „There has been a national committee meet to look at this and to make decisions on the basis of the best scientific evidence available … the evidence is that the strategy has not been effective.”

http://www.news.com.au/breaking-news/states-ending-free-parent-whooping-vaccine/story-e6frfku0-1226350174856

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(Vaccine failure in Atlanta):

Whooping cough vaccine not as powerful as thought.

„Of the 18 students in the recent Cobb cluster, 17 were properly immunized with five doses of DTaP vaccine…”

http://web.archive.org/web/20100612143341/http://www.ajc.com/health/content/metro/stories/2009/03/22/whooping_cough_vaccine.html

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(Wisconsin vaccine failure):

“Kurt Eggebrecht with the Appleton Health Department says there are now 216 confirmed cases and nearly all of those who got sick are children who were vaccinated.”

http://web.archive.org/web/20120825011532/http://www.wbay.com/story/19355251/2012/08/23/whooping-cough-cases-jump-in-appleton
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(Vaccine failure in NY):

„179 reported cases in Suffolk County, NY – according to Suffolk health officials, all those affected had been immunized in the past.”

http://www.nbcnewyork.com/news/local/Whooping-Cough-Triple-Suffolk-County-Long-Island-132659533.html?fb_comment_id=fbc_10150370350412500_19430267_10150380172037500#fb6dbdf11bd1de
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(Mainstream study documents vaccine causing mutation, spreading of whooping cough):

Acellular pertussis vaccination enhances B. parapertussis colonization

„….vaccination led to a 40-fold enhancement of B. parapertussis colonization in the lungs of mice…..these data suggest that the vaccine may be contributing to the observed rise in whooping cough incidence over the last decade by promoting B. parapertussis infection.”

http://www.cidd.psu.edu/research/synopses/acellular-vaccine-enhancement-b.-parapertussis

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(Vaccine has caused bacteria to mutate……this is causing outbreaks):

Whooping cough strain now immune to vaccine – –

“The bacteria that causes whooping cough has mutated, eroding the protection provided by the vaccine now given to children, scientists warned yesterday. Our findings suggest that the use of the acellular vaccine may be one factor contributing to these genetic changes.”

http://www.dailytelegraph.com.au/news/whooping-cough-strain-now-immune-to-vaccine/story-e6freuy9-1225828959714

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(Proof that the vaccine is CAUSING outbreaks and making cases more severe):

(Excerpt): “An acellular vaccine – introduced in Australia in 1997 – appeared to have promoted the spread of these variants, Dr Lan said, which overseas authorities had linked to „higher virulence on the basis of hospitalisation and case mortality data”.

http://www.smh.com.au/national/health/whooping-cough-beats-vaccine-20120320-1vibp.html

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Pomimo wysokiego poziomu pokrycia szczepieniami przeciw krztuścowi, jego cyrkulacja w środowisku nie może być sterowana w ogóle. Wyniki kwestionują skuteczność obecnych programów szczepień. Warto przypomnieć, zanim rozpalą stosy i rozpętają kolejną histerię pt – ”Powrót krztuśca”, który nigdy i nigdzie nie odszedł.
http://www.ncbi.nlm.nih.gov/pubmed/?term=24216286

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Po drugie „The etiologic agent of pertussis, Bordetella pertussis, is extremely monomorphic and its ability to persist in the face of intensive vaccination is intriguing. Numerous studies have shown that B. pertussis populations changed after the introduction of vaccination suggesting adaptation.
The earliest adaptations resulted in antigenic divergence with vaccine strains. More recently, strains emerged with INCREASED PERTUSSIS TOXIN (Ptx) production.
The adaptation of B. pertussis to primed hosts involved delaying an effective immune response by antigenic divergence with vaccine strains and by increasing immune suppression through higher levels of PERTUSSIS TOXIN production. Higher levels of PERTUSSIS TOXIN may also benefit transmission by enhancing clinical symptoms.”
http://www.ncbi.nlm.nih.gov/pubmed/19879977

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Po trzecie „vaccinating individuals in close contact with infants too young to receive the vaccine („cocooning” unvaccinated children) may be ineffective.”
„Recent studies have suggested a fourth mechanism: asymptomatic transmission from individuals vaccinated with the currently used acellular B. pertussis vaccines.
RESULTS:
We find that: 1) the timing of changes in age-specific attack rates observed in the US and UK are consistent with asymptomatic transmission; 2) the phylodynamic analysis of the US sequences indicates more genetic diversity in the overall bacterial population than would be suggested by the observed number of infections, a pattern expected with asymptomatic transmission; 3) asymptomatic infections can bias assessments of vaccine efficacy based on observations of B. pertussis-free weeks; 4) asymptomatic transmission can account for the observed increase in B. pertussis incidence; and 5) vaccinating individuals in close contact with infants too young to receive the vaccine („cocooning” unvaccinated children) may be ineffective.
CONCLUSIONS:
Although a clear role for the previously suggested mechanisms still exists, asymptomatic transmission is the most parsimonious explanation for many of the observations surrounding the resurgence of B. pertussis in the US and UK. These results have important implications for B. pertussis vaccination policy and present a complicated scenario for achieving herd immunity and B. pertussis eradication.
http://www.ncbi.nlm.nih.gov/pubmed/26103968

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